SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany

Rewers, M., Bonifacio, E., Ewald, D., Rasmussen, C.G., Jia, X., Pyle, L., Ziegler, A.G., ASK Study Group and Fr1da Study Group, 2022.

PAPER DETAILS


TITLE

SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany

CATEGORY

Prevalence

DISEASE

Diabetes

ABSTRACT

An increased incidence of clinical diabetes has been reported in children with previous COVID-19.1,2 It is plausible that the virus may trigger autoimmune response to the islets or hasten metabolic decompensation in persons with already established islet autoimmunity. We tested the hypothesis that previous SARS-CoV-2 infection was associated with autoimmunity, which predicts future type 1 diabetes.


AUTHOR(S)

Rewers, M., Bonifacio, E., Ewald, D., Rasmussen, C.G., Jia, X., Pyle, L., Ziegler, A.G., ASK Study Group and Fr1da Study Group, 2022.

JOURNAL

Jama

PLACE

Colorado, USA, and Bavaria, Germany