Risk factors for mortality among COVID-19 patients
Cardiovascular, Diabetes, Kidney disease
COVID-19 is a current global pandemic. However, comprehensive global data analyses for its mortality risk factors are lacking. The current investigation aimed to assess the predictors of death among COVID-19 patients from worldwide open access data.
A total of 828 confirmed cases of COVID-19 with definite outcomes were retrospectively identified from open access individual-level worldwide data. Univariate followed by multivariable regression analysis were used to evaluate the association between potential risk factors and mortality.
Majority of the patients were males 59.1% located in Asia 69.3%. Based on the data, older age (adjusted odds ratio (aOR), 1.079; 95% confidence intervals (95% CI), 1.064–1.095 per year increase), males (aOR, 1.607; 95% CI, 1.002–2.576), patients with hypertension (aOR, 3.576; 95% CI, 1.694–7.548), diabetes mellitus (aOR, 12.234; 95% CI, 4.126–36.272), and patients located in America (aOR, 7.441; 95% CI, 3.546–15.617) were identified as the risk factors of mortality among COVID-19 patients.
Males, advanced age, hypertension patients, diabetes mellitus patients, and patients located in America were the independent risk factors of death among COVID-19 patients. Extra attention is required to be given to these factors and additional studies on the underlying mechanisms of these effects.
Orwa Albitar, Rama Ballouze, Jer Ping Ooi, and Siti Maisharah Sheikh Ghadzia
Diabetes Research and Clinical Practice